Developing a utility index for the Aberrant Behavior Checklist (ABC-C) for fragile X syndrome

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Longitudinal trajectories of aberrant behavior in fragile X syndrome.

The Aberrant Behavior Checklist-Community (ABC-C; Aman et al., 1995) has been increasingly adopted as a primary tool for measuring behavioral change in clinical trials for individuals with fragile X syndrome (FXS). To our knowledge, however, no study has documented the longitudinal trajectory of aberrant behaviors in individuals with FXS using the ABC-C. As part of a larger longitudinal study, ...

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Developing a Critical Checklist for Textbook Evaluation

This study has been carried out to develop a critical checklist for global/commercial textbooks which play a crucial role in language teaching/learning. For this aim, a number of items have been developed based on a comprehensive review of the related literature and experts’ opinions. The tentative checklist was administered to the targeted population, yet 326 checklists were deemed appropriate...

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Cortisol and behavior in fragile X syndrome.

OBJECTIVE The purpose of this study was to determine if children with fragile X syndrome, who typically demonstrate a neurobehavioral phenotype that includes social anxiety, withdrawal, and hyper-arousal, have increased levels of cortisol, a hormone associated with stress. The relevance of adrenocortical activity to the fragile X phenotype also was examined. METHOD One hundred and nine childr...

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Profiles of aberrant white matter microstructure in fragile X syndrome

Previous studies attempting to quantify white matter (WM) microstructure in individuals with fragile X syndrome (FXS) have produced inconsistent findings, most likely due to the various control groups employed, differing analysis methods, and failure to examine for potential motion artifact. In addition, analyses have heretofore lacked sufficient specificity to provide regional information. In ...

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ژورنال

عنوان ژورنال: Quality of Life Research

سال: 2014

ISSN: 0962-9343,1573-2649

DOI: 10.1007/s11136-014-0759-8